Pierre Deslongchamps;Ruoxi Lan;Yves Dory;Luc Ouellet;Gilles Berthiaume
发明人:
Pierre Deslongchamps,Yves Dory,Gilles Berthiaume,Luc Ouellet,Ruoxi Lan
申请号：
US13218784
公开号：
US20120046441A1
申请日:
2011.08.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A library of macrocyclic compounds of the formula (I)where part (A) is abivalent radical, a —(CH2)y— bivalent radical or a covalent bond；where part (B) is abivalent radical, a —(CH2)z— bivalent radical, or a covalent bond；where part (C) is abivalent radical, a —(CH2)t— bivalent radical, or a covalent bond； andwhere part (T) is a —Y-L-Z— radical wherein Y is CH2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.
