A method of labeling an intravenous (IV) system is disclosed. The method may begin with obtaining a label. A label may be formed of a polymeric material and include a top, a bottom, and an aperture formed in at least one of the top and the bottom. At least one of the top and the bottom may have an exterior surface. The label may be applied to an IV system by closing the top with respect to the bottom such that at least one of tubing or a port of the IV system is secured within the aperture. A medical professional may then write on the exterior surface of the label a name of a medication to be administered through the IV system.