The invention relates to novel pyrimidinone-based heterocyclic compounds which are parasite growth inhibitors, having the general formula: in which Y is a morpholine chosen from three bridged morpholines, L is a bond or a linker, n = 0 or 1 and R2 is a methyl group when n = 0 and a hydrogen atom when n = 1. Process for the preparation thereof and therapeutic use thereof.本發明係關於新穎之基於嘧啶酮之雜環化合物,其係寄生蟲生長抑制劑,具有通式:其中Y係選自三種橋接嗎啉之嗎啉,L係鍵或連接體,n=0或1,且在n=0時R2係甲基,在n=1時R2係氫原子。本發明亦關於該等化合物之製備方法及其治療用途。