#$%^&*AU2015201589A120150423.pdf#####ABSTRACT In one aspect, a device for performing RIC includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump a manifold in fluid communication with the pump an outlet in fluid communication with the manifold and in removable fluid communication with the inflatable cuff a pressure sensor and a control circuit configured to implement a RIC treatment protocol. In another aspect, a cuff assembly may be adapted to encircle a limb of a subject. The cuff assembly includes an inner layer, an outer layer, and a bladder disposed between the inner layer and the outer layer. The outer layer includes two flexible foam sections spaced apart in a longitudinal direction of the cuff assembly. The outer layer also includes an intermediate section disposed between the two flexible foam sections. The intermediate section may have a greater rigidity than the two flexible foam sections.
