An ultrasound lithotrite comprises a handle main body (1) and a hand-held portion (2) connected to the handle main body (1), and an ultrasound generator (15) is disposed in the handle main body (1). A first channel (111) is disposed on an internal central axis of the handle main body (1), a second channel (211) is disposed on the internal central axis of the hand-held portion (2), and the first channel (111) and the second channel (211) are on the same straight line. The ultrasound lithotrite further comprises an ultrasound forceps (3) connected to the ultrasound generator (15) and passed through the first channel (111) and the second channel (211) for gripping a stone. The back end of the ultrasound forceps (3) is provided with a horizontal limiting slot (32), and the ultrasound forceps (3) are fixed to the hand-held portion (2) through the horizontal limiting slot (32) and are moved horizontally along the first channel (111) and the second channel (211) with the hand-held portion (2).
