METHODES DE REGULATION DE LA PROLIFERATION DE CELLULES SOUCHES / DE LA GENERATION DE CELLULES AUDITIVES DE L'OREILLE INTERNE A L'AIDE D'INHIBITEURS DE LA GSK-3-ALPHA

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专利权人:

FREQUENCY THERAPEUTICS; INC.

发明人:

LOOSE, CHRISTOPHER,MCLEAN, WILL,HARRISON, MEGAN

申请号：

CA3014659

公开号：

CA3014659A1

申请日:

2017.03.02

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Provided are compositions andmethods for inducing the self-renewal ofstem/progenitor supporting cells, including inducingthe stem/progenitor cells to proliferatewhile maintaining, in the daughter cells, thecapacity to differentiate into hair cells, and includingcompositions and methods of usingGSK3-alpha inhibitors, and salts thereof, optionallyin combination with a DifferentiationInhibitor such as a Notch agonist or an HDACinhibitor (e.g., valproic acid).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/