ACCORDING TO THIS INVENTION, A GENE CLUSTER INVOLVED IN THE NON-MEVALONATE PATHWAY OF HEVEA BRASILIENSIS WAS OBTAINED AND NUCLEOTIDE SEQUENCES OF THESE GENES WERE DETERMINED.THE GENE CLUSTER ACCORDING TO THIS INVENTION INVOLVED IN THE IPP BIOSYNTHESIS IN THE NON-MEVALONATE PATHWAY IS INVOLVED IN THE BIOSYNTHESIS OF VITAMIN E AND CAROTENOIDS. THEREFORE, HEVEA BRASILIENSIS OBTAINED BY INTRODUCING THE GENE CLUSTER OF THE PRESENT INVENTION CAN BE EXPECTED TO PRODUCE HIGH-QUALITY RUBBER WITH IMPROVED PERMANENCE.