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Melanocortin receptor ligands
专利权人:
SOCIETE DE CONSEILS DE RECHERCHES ET DAPPLICATIONS SCIENTIFIQUES S.A.S.
发明人:
DONG, ZHENG XIN,MOREAU, JACQUES-PIERRE
申请号:
NZ58080606
公开号:
NZ580806A
申请日:
2006.07.10
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a compound according to formula (I): (R2R3)-A1-c (A2-A3-A4-A5-A6-A7-A8-A9)-A10-R1 wherein: A1 is Arg, D-Arg, Nle or D-Phe A2 is Cys A3 is D-Ala or deleted A4 is His A5 is D-Phe or D-(Et)Tyr A6 is Arg A7 is Trp A8 is b-Ala, Gaba or deleted A9 is Cys, D-Cys or Pen A10 is Thr or deleted and R2 and R3 is, independently for each occurrence, H or acyl provided that (I) either A3 or A8 or both must be present in said compound and (II) said compound is not Ac-Arg-c(Cys-DAla-His-DPhe-Arg-Trp-Cys)-NH2 (SEQ ID NO:50) or a pharmaceutically acceptable salt thereof.
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来源网址:
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