The injection site multi-functional bandage includes a thin, flexible strip of support material with opposing upper and lower surfaces. The support material can be elongated with adhesive portions at opposing ends thereof. The adhesive portions can be covered by a removable cover. A non-adhesive absorbent can be provided between the adhesive portions on the lower surface of the support material. A reservoir including sterilization liquid can be disposed above or below the absorbent. The reservoir can be positioned along a center portion of the support material. An opening can extend through a portion of the absorbent. The opening can be selectively sealable by a releasable flap.