SLEEMAN, MARK W,MARTIN, JOEL H,HUANG, TAMMY T,MACDONALD, DOUGLAS
申请号:
NZ60192309
公开号:
NZ601923A
申请日:
2009.12.15
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
601923 Provided is a human antibody or antigen-binding fragment of a human antibody that specifically binds and inhibits human proprotein convertase subtilisin/kexin type 9 (hPCSK9), with specified CDR sequences. Further provided are corresponding protein coding DNA sequences and vectors expressing the protein. The antibodies can be used to cholesterol related and cardiovascular diseases.