KIM, Byung Gyu,김병규,KANG, Young-Gyu,강영규,KIM, Soo Hyun,김수현,PARK, Chan Woong,박찬웅,JEON, Hee Young,전희영
申请号：
KRKR2016/004828
公开号：
WO2017/003086A1
申请日:
2016.05.09
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a composition for inhibiting and preventing myopathy, containing a bean leaf extract as an active ingredient and, more specifically, contains an extract of bean leaves in R6 to R8 stages among the growth stages of beans so as to inhibit the overexpression of Atrogin1 and Murf1, which are specifically expressed in myocytes, and restore the cell vitality of myocytes, thereby having an effect of inhibiting and preventing muscle loss.La présente invention concerne une composition permettant d'inhiber et de prévenir la myopathie, contenant un extrait de feuilles de haricot en tant que principe actif et, plus spécifiquement, contenant un extrait de feuilles de haricot issues des stades R6 à R8 parmi les stades de croissance des haricots de manière à inhiber la surexpression de Atrogin1 et Murf1, qui sont spécifiquement exprimés dans les myocytes, et à rétablir la vitalité cellulaire des myocytes, la composition ayant ainsi un effet d'inhibition et de prévention de la perte musculaire.본 발명은 콩잎 추출물을 유효성분으로 함유하는 근질환 억제 및 예방용 조성물에 관한 것으로, 더욱 상세하게는 콩의 생육 단계 중 R6 내지 R8 단계의 콩잎 추출물을 포함함으로써 근세포에 특이적으로 발현하는 Atrogin1 및 Murf1의 과발현을 억제하고 근세포의 세포활성을 회복함으로써 근손실을 억제하고 예방하는 효과가 있다.
