The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1-phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof.本發明係關於磷酸二酯酶4(PDE4)酵素抑制劑。特定言之,本發明係關於屬於1-苯基-2-吡啶烷基醇之衍生物之化合物、此等化合物之製備方法、含有此等化合物之組成物及其治療用途。