RUF SVEN,SADOWSKI THORSTEN,WIRTH KLAUS,SCHREUDER HERMAN,BUNING CHRISTIAN
申请号：
NZ61367212
公开号：
NZ613672A
申请日:
2012.01.26
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
The disclosure relates to substituted 3-heteroaroylamino-propionic acid derivatives of formula (I), wherein the variables A, D, E, L, G, R10, R30, R40, R50 and R60 have the meanings indicated in the specification. These compounds are inhibitors of the protease cathepsin A, and are useful for the treatment of diseases such as atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases, for example. The disclosure furthermore relates to processes for the preparation of the compounds of the formula (I), their use and pharmaceutical compositions comprising them.
