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פולימורפיזם גבישי של מפעיל תעלה kcnq 2-5
专利权人:
ONO PHARMACEUTICAL CO. LTD.
发明人:
申请号:
IL26243918
公开号:
IL262439D0
申请日:
2018.10.17
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
Crystal polymorphism may exist in a crystalline compound. In the case where crystal polymorphism exists, depending on the crystal form, solubility, dissolution rate, stability against heat, light, humidity, etc. or the like is different. Accordingly, in the production of a pharmaceutical product, it is a very important task to select a crystal form of a drug substance most suitable for a disease indication and a dosage form. The present invention relates to novel crystal forms (A crystal, W crystal, and a hydrate crystal (H crystal)) of a compound I having a strong opening action with respect to KCNQ2-5 channels.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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