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DIAGNOSTIC METHODS FOR PAR4 ANTAGONIST THERAPY
专利权人:
发明人:
Jing YANG,Willem H. OUWEHAND
申请号:
US15031941
公开号:
US20160274108A1
申请日:
2014.10.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The disclosure provides methods for identifying a PAR4 agonist responder or a PAR4 antagonist responder comprising contacting a PAR4 agonist with platelets in a sample obtained from a subject in need thereof. The methods also include administering a PAR4 antagonist to the subject identified as a PAR4 agonist responder or a PAR4 antagonist responder. The invention also includes methods of treating the subjects and a pharmaceutical kit comprising a PAR4 agonist.
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