For the treatment of cognitive impairment (cognitiveimpairment), combined serotonin reuptake, as a compound having 5-HT3 and 5-HT1A activity 1- [2- (2,4-dimethyl-phenylsulfanyl) - phenyl] piperazine
1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT 3 and 5-HT 1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.