カテプシンE特異的阻害剤
- 专利权人:
- 独立行政法人科学技術振興機構
- 发明人:
- 西垣 功一,北村 幸一郎,高橋 陽子,山本 健二
- 申请号：
- JP2006166952
- 公开号：
- JP4979992B2
- 申请日:
- 2006.06.16
- 申请国别(地区):
- JP
- 年份:
- 2012
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a substance that specifically inhibits cathepsin E while does not inhibit cathepsin D as a lysosomal enzyme highly analogous to cathepsin E, and a cathepsin E-inhibitor.
SOLUTION: The peptide exhibits inhibiting actions on cathepsin E activities while substantially no inhibiting actions on cathepsin D activities, and has the number of amino acids within the range of 6-34. The cathepsin E-inhibitor comprises the peptide as an effective ingredient. These are obtained from a peptide library prepared by a molecule selection operation using an in-vitro-virus method.
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- 来源网站：
- 中国工程科技知识中心
