MANNA VASANT KUMAR,SEGURA SANDRINE,BUSSARD LUDOVIC,ETCHEGARAY JEAN PIERRE,FREIDENREICH PHILIP
申请号:
IN2063/KOLNP/2014
公开号:
IN2014KN02063A
申请日:
2014.09.29
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
An improved method for treating acne is described. The method involves 16-week, once daily, oral administration of about 40 mg doxycycline in a pharmaceutical composition containing about 30 mg doxycycline in an immediate release portion and about 10 mg doxycycline in a delayed release portion. It was surprisingly discovered that the 16-week, once daily, oral administration of about 40 mg doxycycline has achieved same or superior efficacy than that of 100 mg doxycycline, but with a significant reduction in adverse events.