ADELMAN, STEVEN JAY,SKERRETT, H. DONLON,KINNEY, WILLIAM A.
申请号:
CA2988593
公开号:
CA2988593A1
申请日:
2016.06.15
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to compounds, and methods of use thereof, capable of entering macrophages. The invention further relates to compounds capable of modulating (for example inhibiting) the activity of the mammalian target of rapamycin (mTor), treating mTor-associated diseases, in particular, but not limited to, related to mTor in macrophages. The invention also relates to compounds capable of imaging mTor in a subject, in particular, but not limited to, mTor in macrophages.