James William West,Jason Gary Sagert,Daniel Robert Hostetter,Stephen James Moore,Margaret Thy Luu Nguyen,Olga Vasiljeva,Jeanne Grace Flandez
申请号：
US14036973
公开号：
US09487590B2
申请日:
2013.09.25
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to interleukin-6 receptor (IL-6R), and to methods of making and using these anti-IL-6R activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
