The present invention concerns the use of formic acid and at least one C1-C4 alkyl ester of lactic acid, preferably ethyl lactate, for the manufacture of a composition for the topical treatment of warts. The inclusion in the composition of at least one C1-C4 alkyl ester of lactic acid, preferably ethyl lactate, reduces the contact angle of the composition, i.e. reduces the surface tension. Decreased contact angle makes it easier for the composition to adhere to warts, and following to be absorbed by warts, i.e. improving the penetration of the composition of the invention. Additionally, reduced surface tension makes it easier to apply the composition in the adequate amount, with reduced risk of inadvertently smearing composition on adjacent, healthy skin.