The present application provides anti-LAG-3 constructs comprising a single-domain antibody (sdAb) that specifically recognizes LAG-3. Also provided are methods of making and using these constructs.本申請案提供抗LAG-3構築體,其包含特異性識別LAG-3之單一結構域抗體(sdAb)。亦提供製備及使用該等構築體之方法。