IFOM - FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE
发明人:
D'ADDA DI FAGAGNA, FABRIZIO,ROSSIELLO, FRANCESCA,AGUADO, JULIO,JONES-WEINERT, COREY,DADDA DI FAGAGNA, FABRIZIO
申请号：
CA2993128
公开号：
CA2993128A1
申请日:
2016.07.29
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention relates to an oligonucleotide comprising one of the following sequence: (TTAGGG) SEQ ID No. 1, (TAGGGT) SEQ ID No. 2, (AGGGTT) SEQ ID No. 3, (GGGTTA) SEQ ID No. 4, (GGTTAG) SEQ ID No. 5 or (GTTAGG) SEQ ID No. 6 or a complementary sequence thereof or a fragment or a variant or a mixture thereof for use in the treatment and/or prevention of a disease characterized by alternative lengthening of telomeres or a non-cancer condition associated with telomere dysfunction and relative pharmaceutical compositions and to relative pharmaceutical composition and method.
