[Problem]To provide a medical use honeycomb structure that satisfies demands desired of a medical use material, namely: (1) having excellent adhesiveness or binding of a cell or a tissue to a material surface; (2) can regenerate/reconstruct an oriented tissue; (3) having excellent mechanical strength; (4) when used as a tissue replacement material, quickly replacing a desired tissue; and (5) being able to be produced at a low cost.[Solution]A medical use honeycomb structure comprising a plurality of through-holes extending in one direction, wherein an outer peripheral section of the medical use honeycomb structure has a through-hole groove formed by incomplete side walls of the through-hole, and a through-hole inlet adjacent to the through-hole groove.