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DÉRIVÉ DE 2,3-DIHYDRO-1H-INDÈNE-2-YLURÉE ET SON APPLICATION PHARMACEUTIQUE
专利权人:
Toray Industries; Inc.
发明人:
申请号:
EP10820624.4
公开号:
EP2484661B1
申请日:
2010.09.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
In order to provide a low molecular weight compound that has p38MAPK inhibitory activity and the accompanying TNF± production suppression activity and that has a favorable pharmacokinetic profile as a pharmaceutical and decreased hepatotoxicity, and to provide a pharmaceutical application of same, disclosed is a 2,3-dihydro-1H-indene-2-yl urea derivative represented below, a pharmacologically acceptable salt thereof, and a therapeutic agent or preventative agent that contains same as an active ingredient and that is for allergic dermatitis, inflammatory bowel disease, and pain.
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