COMPOSES DE 1H-INDAZOLE-3-CARBOXAMIDE UTILISES EN TANT QU'INHIBITEURS DE LA GLYCOGENE SYNTHASE KINASE 3 BETA

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专利权人:

AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO - A.C.R.A.F. S.P.A.

发明人:

FURLOTTI, GUIDO,CAVARISCHIA, CLAUDIA,BUONFIGLIO, ROSA,OMBRATO, ROSELLA,IACOANGELI, TOMMASO

申请号：

CA3094896

公开号：

CA3094896A1

申请日:

2019.05.06

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present invention relates to the 1 H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3ß) inhibitors and to their use in the treatment of GSK-3ß-related disorders such as, for example, (i) insulin-resistance disorders； (ii) neurodegenerative diseases； (iii) mood disorders； (iv) schizophrenic disorders； (v) cancerous disorders； (vi) inflammation, (vii) osteoporosis, (viii) cardiac hypertrophy, (ix) epilepsies and (x) neuropathic pain.

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