A multifunctional enclosure for medical probes and particularly an elongated probe member such as endoscope probe is described. The multifunctional enclosure provides an elongated sleeve that is configured to extend over a medical probe for the purpose of protecting the probe during transport and/or sterilization. An elongated sleeve may also provide a reservoir for pre-treating the medical probe with fluids or gels and may also provide a reservoir for quickly treating a medical probe with disinfectant or cleaning solution following a procedure. A multifunctional enclosure may comprise an handle housing that is configured to enclose at least a portion of a medical probe handle. An elongated sleeve may be detachable from a handle housing portion of a multifunctional enclosure and a liner may installed inside of the elongated sleeve.