SELS DE 3-(3-AMINO-2-(R)-HYDROXY-PROPYL)-1-(4-FLUORO-PHENYL)-8-(8-METHYL-NAPHTALEN-1-YLMETHYL)-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE

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专利权人:

JANSSEN PHARMACEUTICA N.V.

发明人:

MEHRMAN, STEVEN J.,ROESSLER, ARMIN,FAESSLER, ROGER,VILLANI, FRANK J.,HEGYI, JEAN FRANCOIS ALEXANDRE LUCAS

申请号：

CA2670858

公开号：

CA2670858C

申请日:

2007.11.14

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention is directed to salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by NOP, for example depression, anxiety, alcohol abuse, etc. The present invention is further directed to process(es) for the preparation of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one and its corresponding salts.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/