Raitano, Arthur B.,Morrison, Karen,Hubert, Rene S.,Jakobovits, Aya,Morrison, Robert Kendall,Ge, Wangmao,Challita-Eid, Pia M.,Faris, Mary
申请号:
AU2007237282
公开号:
AU2007237282B2
申请日:
2007.11.30
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2007237282B220120315.pdf#####ABSTRACT A novel gene (designated 162PlE6) and its encoded protein, and variants thereof, are described wherein 162P1E6 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 162P1E6 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 162P1E6 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response antibodies or T cells reactive with 162P1E6 can be used in active or passive immunization.