Jon A. Weidanz,Kimberlyn F. Card,Linda A. Sherman,Norman R. Klinman,Hing C. Wong
申请号:
US13335362
公开号:
US20120230995A1
申请日:
2011.12.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to polyspecific binding molecules and particularly single-chain polyspecific binding molecules that include at least one single-chain T-cell receptor (sc-TCR) covalently linked through a peptide linker sequence to at least one single-chain antibody (sc-Ab). Further disclosed are methods and compositions for testing and using the molecules.