The invention relates to devices and methods for visualizing and/or interacting with internal body tissues. More particularly, the present invention relates to endoscopic methods and devices for visualizing and/or interacting with the gastrointestinal and/or pancreaticobiliary systems, such as with one use or disposable devices, such as with duodenoscopes. A device for visualizing and/or interacting with internal body tissues may generally include a handpiece, a distal assembly, and/or a connecting conduit. A plurality of conduits and/or channels may span through the connecting conduit from the handpiece to the distal assembly, and may, for example, carry fluid/gas connections, electrical/sensor connections, such as for a camera, mechanical connections and/or carry medical devices through a working channel. The device may also reduce the needs associated with reusable devices such as for reducing risks associated with improper sterilization.
