Brendan J. CASEY,Peter KOFINAS,Adam BEHRENS,Trevor A. SNYDER,Bartley P. GRIFFITH
申请号:
US14505905
公开号:
US20150030664A1
申请日:
2014.10.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present application is drawn to a synthetic, polymer hydrogel-based material, which is able to actively induce the bodys natural hemostatic coagulation process in blood or acellular plasma. The present invention provides the development of a primary amine containing polymer hydrogel capable of inducing blood coagulation and delivering therapeutics for hemostatic or wound care applications, and a method of forming such a primary amine containing polymer hydrogel capable of inducing the blood coagulation process. The primary amine containing polymer hydrogel is able to achieve the same end result as biological-based hemostatics, without the innate risk of disease transmission or immunological response, and at a fraction of the price. Furthermore, due to its inherent hydrogel-based design the material has the capability of arresting blood loss while simultaneously delivering therapeutics in a controlled manner, potentially revolutionizing the way in which wounds are treated.