This invention describes methods of Audio Signal Personalized Enhancement for optimal listening to music. A combination of hearing test, audio signal compensation, and signal processing algorithms are implemented jointly in an audio Device. An audio signal is processed and tuned within the entire range of audible frequencies to actively compensate for both the characteristics of the listening device, and the specific hearing characteristics of the listener, resulting in a much improved music listening experience. A randomized self-test algorithm is used to analyze user's hearing ability in each ear within a preselected dynamic volume range at multiple frequencies spanning the audible spectrum.