PROBLEM TO BE SOLVED: To provide a new dental caries prevention agent that has no influence over oral indigenous bacteria.SOLUTION: By a biofilm formation inhibitor comprising one or more of natto, isolated Bacillus natto, or a culture filtrate of isolated Bacillus natto as an active ingredient, provided is a new dental caries prevention agent that has no influence over oral indigenous bacteria.COPYRIGHT: (C)2015,JPO&INPIT【課題】口腔常在菌に影響を及ぼさない、新たなう蝕予防剤の提供を課題とする。【解決手段】納豆、納豆分離菌、または納豆分離菌培養濾液のいずれか一種以上を有効成分とするバイオフィルムの形成抑制剤により、口腔常在菌に影響を及ぼさない、新たなう蝕予防剤を提供する。【選択図】なし
