PROBLEM TO BE SOLVED: To provide a medical rubber plug manufactured by a simple method and having high chemical resistance and airtightness.SOLUTION: The medical rubber plug is sealed by a cap that has a compressing annular protrusion 4 along an outer peripheral edge of a flange part of a rubber plug, and in which a leg part 1 coming into contact with a medicament and a lower surface of a flange 2 are laminated with a continuous inactive film 3. The medical rubber plug is molded by a single step, with a surface area from the outer edge part of the flange lower surface of the rubber plug is 50% or more, and surface roughness Ra in an area from an uppermost part of a leg part-side upper part to 1-5 mm below with the topmost defined as an origin is 0.1 μm or less.COPYRIGHT: (C)2014,JPO&INPIT【課題】製造方法が簡便である、耐薬品性と気密性に優れた医療用ゴム栓を提供する。【解決手段】ゴム栓のフランジ部外周縁に沿って圧縮用環状凸部4を有し、薬剤と接する脚部1及びフランジ2下面が連続した不活性フィルム3で積層された、キャップでシールされる医療用ゴム栓であって、ゴム栓のフランジ下面の外縁部より表面積が50%以上、かつ、脚部側面上部の最上部から、最上部を起点に1~5mmまでの領域の表面粗さRaが0.1μm以下である一段成型された医療用ゴム栓に関する。【選択図】図1