indole carboxamide derivatives as p2x7 receptor antagonists

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专利权人:

ACTELION PHARMACEUTICALS LTD

发明人:

DORTE RENNEBERG,FRANCIS HUBLER,KURT HILPERT,SIMON STAMM,THIERRY KIMMERLIN

申请号：

BR112015013463

公开号：

BR112015013463A2

申请日:

2013.12.11

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

Indole carboxamide derivatives as p2x7 receptor antagonists The invention relates to the indole carboxamide derivatives of formula (i), wherein r1, r2, r3, r4, r5 and r6 are as defined in description, in their preparation and their use as pharmaceutically active compounds.1/1 resumo derivados de carboxamida indol como antagonistas do receptor de p2x7 a invenção refere-se aos derivados de carboxamida indol da fórmula (i), (i) em que r1, r2, r3, r4, r5 e r6 são como definidos na descrição, na sua preparação e seu uso como compostos farmaceuticamente ativos.

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