TAYLOR, CHARLES A.,GRADY, LEO,SANKARAN, SETHURAMAN,SENGUPTA, SOUMA,KIM, HYUN JIN,XIAO, NAN
申请号:
CA2991784
公开号:
CA2991784A1
申请日:
2016.07.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Systems and methods are disclosed for assessing the severity of plaque and/or stenotic lesions using contrast distribution predictions and measurements. One method includes: receiving patient-specific images of a patients vasculature and a measured distribution of a contrast agent delivered through the patients vasculature associating the measured distribution of the contrast agent with a patient-specific anatomic model of the patients vasculature defining physiological and boundary conditions of a blood flow model of the patients blood flow and pressure simulating the distribution of the contrast agent through the patient-specific anatomic model comparing the measured distribution of the contrast agent and the simulated distribution of the contrast agent through the patient-specific anatomic model to determine whether a similarity condition is satisfied and updating the defined physiological and boundary conditions and re-simulating distribution of the contrast agent through the one or more points of the patient-specific anatomic model until the similarity condition is satisfied.