Arlene H. Sharpe,Gordon J. Freeman,Loise M. Francisco,Peter T. Sage,Sun J. Lee,Scott B. Lovitch,Vikram R. Juneja,Catherine L. Tan
申请号:
US15768077
公开号:
US20180303922A1
申请日:
2016.10.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention is based, in part, on the identification of methods of modulating PD-1 expression and/or activity in regulatory T cells (Tregs) to thereby regulate effector immune responses in effector T cells (Teffs).