#$%^&*AU2018267584A120200604.pdf#####49 ABSTRACT A composition suitable for therapeutic or prophylactic treatment of one or more conditions in a subject is provided, the composition comprising one or more vitamins; one or more metals; one or more amino acids; and/or one or more plant extracts. The 5 condition may be a hangover symptom. Associated methods of manufacture of compositions, and methods of treatment are also provided. S 1 AA- 1