Astraea Therapeutics, LLC;Zaveri, Nurulain, T.;Meyer, Michael;Journigan, V., Blair;Yasuda, Dennis
发明人:
ZAVERI, Nurulain, T.,MEYER, Michael,JOURNIGAN, V., Blair,YASUDA, Dennis
申请号:
EP16871683
公开号:
EP3383390A4
申请日:
2016.12.02
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention provides novel piperidinyl-containing nociceptin receptor ligand compounds and pharmaceutical compositions useful in the treatment of neurological diseases and conditions where such ligands mediate the negative effects of the condition. Such neurological diseases and conditions include acute and chronic pain, substance abuse/dependence, alcohol addiction, anxiety, depression, sleep disorders, gastrointestinal disorders, renal disorders, cardiovascular disorders and Parkinson' s disease.