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Albumin-purification method comprising a nanofiltration step, solution, and composition for therapeutic use containing the same
专利权人:
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
发明人:
Paul Boulange,Sami Chtourou,Stephane Boyer,Roland Schmitthaeusler,Bruno Padrazzi
申请号:
US15443884
公开号:
US10562957B2
申请日:
2017.02.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to an albumin-purification method comprising a step consisting in subjecting an aqueous albumin solution, with a concentration of between 15 g/l and 80 g/l and a pH of not less than 7, to nanofiltration in a temperature range of between 15 DEG C. and 55 DEG C. The invention also relates to: a virally-safe aqueous albumin solution which can be obtained using the inventive method and in which the sites for the transport and binding of the active therapeutic ingredients of the albumin are available; and an albumin composition for therapeutic use, which is obtained by adapting the albumin solution that is intended for clinical use.
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