New topical medicaments are provided. The medicaments comprise menthol andcamphor, preferably provided as part of a base gel, supplemented withpotassium and a source of oxygen. The most preferred base gel is sold underthe name SOMBRA, while the most preferred source of oxygen is a chlorite(e.g., sodium chlorite) and/or spirulina. The medicaments provide highmetabolic activities and sustain those activities over prolonged periods oftime, thus being useful for treating a large variety of aliments, includingdiabetic neuropathy, post hepatic neuralgia, sclerodema, psoriasis, strain,spasticity, headaches, neuropathy secondary to drugs, peripheral neuropathy,leg pain, muscle cramps, muscle aches and pains, bruise, sinusitis, sprain,arthritis, joint pain (arthralgia), and edema.