Mixtures of vitamin E and polyunsaturated fatty acids (PUFAs) are provided as agents for the prevention, control and/or treatment of conditions associated with excessive fat accumulation in the liver which is not caused by alcohol abuse, including control and/or treatment of non-alcoholic steatosis in the liver—；known as non-alcoholic fatty liver disease (NAFLD)—；and/or non-alcoholic steatohepatitis (NASH) in a subject in need thereof.
