KERSTIN LINDBLAD-TOH,LOUIS M. KUNKEL,NATASSIA M. VIEIRA,MAYANA ZATZ
申请号：
US15519100
公开号：
US20170224758A1
申请日:
2015.10.16
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are compositions and methods of treating muscular dystrophy (MD), such as administering an effective amount of a composition that increases the expression of JAG1, a composition comprising a JAG1 agonist, or a composition that promotes JAG1 signaling. Also provided are methods of prognosing MD or evaluating responsiveness to treatment for MD, e.g., by measuring an expression level of JAG1, and methods of identifying a compound for the treatment of MD.
