PROBLEM TO BE SOLVED: To give a feeling of security to an operator regarding an endoscope system for irradiating an observed site of a subject with light different in wavelength band to acquire information on matter of interest present at the observed site.SOLUTION: The observed site of the subject is irradiated with a plurality of light different in wavelength band. Reflected light from the observed site is imaged by a CCD 35, and reflection spectra S are computed by a reflection spectrum computing section 80 based on imaging signals output from the CCD 35. A multiple regression analysis section 81 makes a multiple regression analysis of the reflection spectra S and absorption spectra (an) of the matter of interest such as blood and hemoglobin and matter of non-interest such as bile and staining matter. An eliminating section 83 eliminates spectral components of the matter of non-interest obtained by the multiple regression analysis, from the reflection spectra S. A blood vessel information acquiring section 84 acquires blood vessel information such as oxygen saturation and blood vessel depth based on the reflection spectra S from which the spectral components of the matter of non-interest are eliminated. Blood vessel information images acquired based on the reflection spectra S, S are displayed in parallel on a monitor 19.COPYRIGHT: (C)2012,JPO&INPIT【課題】術者に安心感を与える。【解決手段】被検体の被観察部位に異なる波長帯域の複数の光を照射する。被観察部位からの反射光をCCD35で撮像し、CCD35から出力された撮像信号を元に反射スペクトル算出部80で反射スペクトルSを算出する。重回帰分析部81は、反射スペクトルSと血液やヘモグロビン等の関心物質および胆汁や染色物質等の非関心物質の吸収スペクトルanの重回帰分析を行う。除去部83は、重回帰分析より求めた非関心物質のスペクトル成分を反射スペクトルSから除去する。血管情報取得部84は、非関心物質のスペクトル成分が除去された反射スペクトルS’に基づいて酸素飽和度や血管深さ等の血管情報を取得する。モニタ19には、反射スペクトルSおよびS’を元に取得した血管情報画像が並列表示される。【選択図】図9