PROBLEM TO BE SOLVED: To provide the production of a biocompatible composition having a capacity of being localized to a peculiar position, a correct long term or short term polymerization time and suitable for in vivo absorption properties or the like, and a using method including a sealant composition.SOLUTION: Disclosed is a phase compatible composition obtained by combining a substrate comprising one or more kinds of proteins selected from albumin, elastin, fibrin and soluble and insoluble collagens and an adhesion modifier and prepared by one or more kinds selected from plasticizers, hydrocarbons and the other modification substances with thermally stabilized glutaraldehyde. The substrate may further include carbohydrate, a filler and polyblend. The composition is applied to a slant installed in a blood vessel part.COPYRIGHT: (C)2014,JPO&INPIT【課題】特異的位置へ局在化される能力、的確な長期又は短期の重合時間、及び適切なインビボ吸収特性等を有する生体適合性組成物の製造及びシーラント組成物用を含む使用法の提供。【解決手段】アルブミン、エラスチン、フィブリン、並びに可溶性型及び不溶性型のコラーゲンの1種又は複数のタンパク質及び接着改質剤を含み、並びに可塑剤、炭水化物、又は他の改質物質の1種又は複数より調製される基体、及び熱安定化されているグルタルアルデヒドを組み合わせた相転化可能な組成物。基体は更に炭水化物、充填材及びポリブレンドを含んでも良い。前記組成物が適用されるのは血管部位に設置するスラントである。【選択図】図2
