A capping device is configured to terminate a connector while disconnected from another connector in a fluid transportation system, e.g., for peritoneal dialysis. The connector comprises an exposed surface portion that is enclosed when the connector is connected to the other connector. The capping device comprises a body defining a chamber with an opening, a liquid-containing disinfectant in the chamber, a sealing element arranged in the opening to form a sealed cavity retaining the disinfectant, and a structure for engaging and guiding the connector towards the body such that a portion of the connector displaces the sealing element into the chamber. The sealed cavity is configured such that a displacement of the sealing element into the chamber actively presses the disinfectant out of the sealed cavity, for disinfecting at least part of the exposed surface portion. The capping device may be manufactured by introducing the liquid-containing disinfectant into the chamber through the opening, and by arranging the sealing element in the opening to form the sealed cavity.
