Gary Owens,Whye-Kei Lye,Michael Reed,Joshua Spradlin,Brian Wamhoff,Matthew Hudson,Kareen Looi
申请号：
US11753134
公开号：
US09770349B2
申请日:
2007.05.24
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates generally to medical devices containing nanoporous surfaces and methods for making same. More specifically, the invention relates to implantable vascular stents or other biomedical devices having at least one dealloyed nanoporous layer that promotes improved cellular adhesion properties that promote healing and long term biocompatibility. In the case of stents, the nanoporous layer promotes re-endothelialization at sites of stent implantation vasculature, improves overall healing, and reduces inflammation and intimal disease progression. The nanoporous layer may be optionally loaded with one or more therapeutic agent to further improve the function of the implanted stent and further augment clinical efficacy.
