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TIMBRE
专利权人:
Sekisui Medical Co.; Ltd.
发明人:
申请号:
EP11838081.5
公开号:
EP2636408A1
申请日:
2011.11.02
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Disclosed is a patch which is a formulation including deposited clonidine crystals and provides stable transdermal absorbability even after storage at varying temperatures. The patch disclosed includes a backing and a medicated layer integrally superposed on one surface of the backing. The medicated layer contains: 5 to 30% by weight of clonidine including clonidine in a crystallized state; 25 to 90% by weight of a macromolecular base (A) having a viscosity-average molecular weight of 800,000 or larger; and 5 to 60% by weight of a liquid additive capable of dissolving the clonidine. The weight ratio of the liquid additive to the macromolecular base (A) [the liquid additive/the macromolecular base (A)] is 0.1 to 2.0.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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