INSTITUTE FOR RESEARCH IN BIOMEDICINE;SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE;SCHWEIZERISCHES TROPEN- UND PUBLIC HEALTH-INSTITUT
发明人:
Antonio LANZAVECCHIA,Joshua Hoong Yu TAN,Claudia DAUBENBERGER,Brandon SACK
申请号：
US16606207
公开号：
US20200093909A1
申请日:
2018.04.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, for example for use in a malaria vaccine. The present invention also provides nucleic acids encoding a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, compositions comprising a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1 and antibodies binding to a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1. The antibodies according to the present invention bind specifically to P. falciparum sporozoites and may be used in the treatment and/or prevention of malaria.
